Insights into human outer kinetochore assembly and force transmission from a structure-function analysis of the KMN network https://www.biorxiv.org/content/10.1101/2023.08.07.552315v1?med=mas
Screening the human druggable genome identifies ABHD17B as an anti-fibrotic target in hepatic stellate cells https://www.biorxiv.org/content/10.1101/2023.08.07.551744v1?med=mas
Recombinant SARS-CoV-2 lacking initiating and internal methionine codons within ORF10 is attenuated in vivo https://www.biorxiv.org/content/10.1101/2023.08.04.551973v1?med=mas
SARS-CoV-2 infection of human pluripotent stem cell-derived vascular cells reveals smooth muscle cells as key mediators of vascular pathology during infection https://www.biorxiv.org/content/10.1101/2023.08.06.552160v1?med=mas
AAV-HBV mouse model replicates immune exhaustion patterns of chronic HBV patients at single-cell level https://www.biorxiv.org/content/10.1101/2023.08.07.552328v1?med=mas
Mucosal and systemic immune dynamics associated with COVID-19 outcomes: a longitudinal prospective clinical study https://www.biorxiv.org/content/10.1101/2023.08.04.551867v1?med=mas
Characterization of m6A modifiers and RNA modifications in uterine fibroids https://www.biorxiv.org/content/10.1101/2023.08.07.552278v1?med=mas
FRET-guided modeling of nucleic acids https://www.biorxiv.org/content/10.1101/2023.08.07.552238v1?med=mas
phuEGO: A network-based method to reconstruct active signalling pathways from phosphoproteomics datasets https://www.biorxiv.org/content/10.1101/2023.08.07.552249v1?med=mas
DNA Nanostructure-Guided Assembly of Proteins into Programmable Shapes https://www.biorxiv.org/content/10.1101/2023.08.07.552347v1?med=mas
Heme exporter FLVCR regulates mitochondrial biogenesis and redox balance in the hematophagous insect Rhodnius prolixus https://www.biorxiv.org/content/10.1101/2023.08.07.552335v1?med=mas
Purifying selection and adaptive evolution proximate to the zoonosis of SARS-CoV-1 and SARS-CoV-2 https://www.biorxiv.org/content/10.1101/2023.08.07.552269v1?med=mas
Discovery of a Well-Folded Protein Interaction Hub Within the Human Long Non-Coding RNA NORAD https://www.biorxiv.org/content/10.1101/2023.08.07.552337v1?med=mas
Genetic Characterization of Glyoxalase Pathway in Oral Streptococci and its Contribution to Interbacterial Competition https://www.biorxiv.org/content/10.1101/2023.08.07.552317v1?med=mas
Impact of Donor Individuality, Temporal Variation, and Culture Medium Type on Microbiota Composition and Metabolic Activity in Human Fecal Batch Culture https://www.biorxiv.org/content/10.1101/2023.08.07.552316v1?med=mas
CD4+ T cell senescence is associated with reduced reactogenicity in severe/critical COVID-19 https://www.biorxiv.org/content/10.1101/2023.08.04.551565v1?med=mas
Molecular basis of Gabija anti-phage supramolecular assemblies https://www.biorxiv.org/content/10.1101/2023.08.07.552356v1?med=mas
Development of a Quorum-Sensing Based Bacterial GMO for Targeted Treatment of Bovine Mastitis. https://www.biorxiv.org/content/10.1101/2023.08.07.552207v1?med=mas
Tissue-specific increases in hypoxia-inducible factor 1 alpha protein are independent of mRNA levels during acute hypoxic exposure of the Gulf killifish, Fundulus grandis https://www.biorxiv.org/content/10.1101/2023.08.07.552360v1?med=mas
Pathogenic entero- and salivatypes harbour changes in microbiome virulence and antimicrobial resistance genes with increasing chronic liver disease severity https://www.biorxiv.org/content/10.1101/2023.08.06.552152v1?med=mas
The non-profit preprint server for the life sciences