We are excited to present our new study combining in vivo CRISPR perturbation sequencing with barcode-based lineage tracing. Our study reveals a mechanism by which selective enhancer activation establishes the identity of GABAergic projection neurons. This work may help to better understand neurologic disease caused by MEIS2 mutations. Thanks to @Elena_dvoretskova, May, Volker, our collaborators, and

Amazing discovery: how motor neurons come to control fast and slow muscles!

Q: How do developing motor neurons decide to be "fast" (controlling fast-twitch, or "sprinting" muscle fibers) or "slow" (endurance)?

A: Genes called transcription factors determine fast motor neuron "fate." Losing factors make fast neurons project to slow muscle & express "slow motor neuron" genes!

Work from my & Jeremy Dasen's lab: biorxiv.org/content/10.1101/20

Pls boost -- trying to beat that other site 🤷🏻‍♂️😝.

Congratulations, Lukas Groschner!

The project leader in Alexander Borst's department receives the Schilling Research Award of the German Neuroscience Society 2023. The prize recognizes his contribution to the understanding of how single neurons perform arithmetic operations.


@lukas @MPIforBI
#science #sciencemastodon #neuroscience #award # scienceaward #mpiforbi

Photo: MPI for Biological Intelligence/Axel Griesch

Please join us in welcoming our new IMPRS-BI: the International Max Planck Research School – Biological Intelligence!

The program will offer first-rate doctoral positions in the fields of neuroscience, neurotechnology, behavioral ecology, connectomics, and evolutionary genetics. The application portal will open soon, stay tuned!

Find out more: imprs-bi.mpg.de/

#mpiforbi #maxplanck #maxplanckinstitute #imprs #imprsbi #gradschool #graduateschool #phdprogram #phd #phdingermany

Congratulations Christian Mayer for successfully joining the EMBO Young Investigator Programme!
The Mayer group develops new approaches to determine genetic mechanisms underlying the differentiation of inhibitory neurons. Learn more: bi.mpg.de/mayer'
#science #ScienceMastodon #embo #neuroscience #mpiforbi

I am very excited to announce that my lab will join the Young Investigator Programme. I am greatly honored to have been selected for this program, and I look forward to interacting with the program's research groups.

I am a Max Planck Research Group Leader at the MPI for Biological Intelligence. Our lab explores fundamental questions in developmental related to the generation of cell-type diversity. We combine scRNAseq with lineage barcoding tools and genetic perturbation to explore principles that orchestrate the establishment of neuronal identities.

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