Wei-Chung Allen Lee @darbly@qoto.org

How can we see what neurons deep in the cortex are doing during behavior? Now all cortical layers of a freely moving mouse can be imaged – even in lit environment. Artwork by @somedonkey https://mpinb.mpg.de/en/research-groups/groups/behavior-and-brain-organization/news/neuroscientists-illuminate-how-brain-cells-deep-in-the-cortex-operate-in-freely-moving-mice.html

3,013 neurons, half a million synapses: the complete #connectome of the whole #Drosophila larval brain!

Winding, Pedigo et al. 2022. "The connectome of an insect brain" https://www.biorxiv.org/content/10.1101/2022.11.28.516756v1

We’ve mapped and analysed its circuit architecture, from sensory neurons to brain output neurons, as reconstructed from volume electron microscopy, and here is what we found. 1/

#neuroscience #connectomics #vEM #volumeEM

Hello Mastodon friends! #Introduction time…

I study neural networks supporting flexible #Navigation at HHMI’s Janelia Research Campus. Using tractable systems, both biological (flies) and artificial (RNNs), I try to link the structure of neural circuits to their underlying function. In grad school, I studied hippocampal ripples at Caltech, and I love searching for shared operating principles across systems/species.

Here are two of my favorite fly neuron types. Aren’t they beautiful? 🙂

"Structured cerebellar connectivity supports resilient pattern separation" Nguyen, Thomas et al. in @darbly's lab https://www.nature.com/articles/s41586-022-05471-w

Spectacular work based on connectomic reconstruction from nanometre-resolution volume electron microscopy and computational modelling that contributes novel findings in cerebellar microcircuitry:

"both the input and output layers of the circuit exhibit redundant and selective connectivity motifs, which contrast with prevailing models. Numerical simulations suggest that these redundant, non-random connectivity motifs increase the resilience to noise at a negligible cost to the overall encoding capacity. This work reveals how neuronal network structure can support a trade-off between encoding capacity and redundancy, unveiling principles of biological network architecture with implications for the design of artificial neural networks."

#cerebellum #connectomics #neuroscience #science #vEM #volumeEM #NeuralBetwork

#introduction
Hi all!
I am an engineer and software developer focused on #opensource tools for #neuroscience research, especially for extracellular #electrophysiology. Core developer of @spikeinterface.

Currently working with the Allen Institute of Neural Dynamics to build efficient and automated pipelines for large-scale ephys analysis. Also working part-time with CatlystNeuro, helping labs to adopt open-source and standard solutions for analysis and data storage.
I'm also interested in biophysical #modeling, #neurotechnology, and #multimodal approaches to probe neural activity.

Hello world! We are Open Ephys. We make #opensource hardware and software for #neuroscience research. We are a worker cooperative (https://en.wikipedia.org/wiki/Worker_cooperative). We want to make scientific tools available to anybody who might want to use them.

Hey everyone! 👋 #introduction
I'm a PhD student in Biostatistics (& Computational Biology) at UC Berkeley. I am interested in statistical modeling and data analysis of single-cell RNA sequencing and imaging data, as well as CRISPR screening.
I’m excited about developing and applying models to learn new biology, esp. immunology and neuroscience.
#womeninstem #FirstGen

I joined Twitter with the attempt to connect the scientific world only at the professional level. I want a #freshstart in Mastodon. I want to be more human, connect to people as a person, and also at the professional level. Here comes the first post about my passion: #cooking. Have you ever tried #popcorn chicken? It is a classical #Taiwanese street food that I often ate as late night snack. I love it so much that I‘d made them myself. Great to go with beer!

#introduction I am Peggy Wei, an #NewPI (3 years old) at #DKFZ . I am also a mother with two children, and a cooking lover. We use #omics and #mousemodel to understand genome integrity and somatic mosaicism in the developing #brain. Other interests include but not limited to #neuropsychiatric disorders , #cancer origin, DNA #replication, #CNV, and #singlemolecule view of DNA damage. I transferred from the other server (@braingenome@scicomm.xyz) because I feel closer to genomics.

And a not unrelated quote from Santiago Ramon Y Cajal.

Some advice from Seymour Benzer that Drosopila, and other neurobiologists, would be wise to remember.

Hello👋 I’m a research fellow and psychiatrist at the University of Cambridge. I work on interactions between the immune system, brain and behaviour esp using #ImmunoGenetics approaches. Interested in #biomarker discovery in psychiatry. Looking forward to discussions on here! #genomics #immunopsychiatry #neuroscience #neuroimmunology #introduction

POSTDOC alert: We're looking for a postdoctoral scientist to join our lab at Dartmouth! We study the neural basis of perception, memory, and neurodiversity using fMRI + VR.

www.robertsonlab.com/current-openings

Learn about the brain and live in the mountains! Please share.

I'm a #neuroscientist in Singapore using #zebrafish to understand appetite control and gut-brain signaling pathways. Check out my lab at www.carolineweelab.com. My other hobbies are hanging out with my two cats, rock climbing, and swimming, but the former is to me wayyy more fun than the latter two New to this app and still rather confused, but happy to try out something new!

#introduction

OK, guess it's time.

I'm Roby, I'm an ID doc at Mass General Hospital in Boston, and a PI with a lab at the Broad Institute that studies antibiotic resistance; and transcriptomics as a comprehensive, quantitative way to understand phenotype of microbes & immune systems under stress; and leverages that for molecular diagnostic development.

Pro: open science, nerdy paper summaries, dad jokes, tennis, coffee, vaccines, kindness, equity, sleep.

Con: AMR, pandemics.