hkl @hkl@qoto.org

Wow, TRISCO (née TRIC-DISCO) is out in Science! This cool approach allows imaging of mRNA transcripts throughout the cleared mouse brain. It uses a signal amplification step with in situ Hybridization Chain Reaction (isHCR) and combines it with DISCO-style solvent-based #tissueclearing to make the brain transparent.

Whole-brain spatial transcriptional analysis at cellular resolution
Kanatani et al., Science 2024
https://doi.org/10.1126/science.adn9947

#neuroscience #lightsheet #microscopy #isHCR #mRNA #TRISCO

Aligning visual prosthetic development with implantee needs https://tvst.arvojournals.org/article.aspx?articleid=2802271 "We interviewed six recipients of the most widely used visual implants (Argus II and Orion)"; #BCI #NeuroTech

"Although implants are designed to facilitate various daily activities, we found that implantees use them less frequently than researchers expect."

"Our study reveals a significant gap between researcher expectations and implantee experiences with visual prostheses."

Took a workshop in multiflash at Owlet Lodge feeders... whatcha think? 🙂

#bird #birds #hummingbird #hummingbirds #BirdPhotography #FlashPhotography #BIFPhotography #BIF #BirdInFlight #NikonZ8 #Nature #Outdoors #GardenGoals

🔴 AI feels like an unstoppable force. But it is not a panacea for businesses or society

Akhil Bhardwaj
Anastasia Sergeeva

"But more worryingly, AI can diminish human capabilities to the extent that the ability to determine when to intervene might be lost. Researchers have found that use of AI leads to skill decay – a particular concern where workplace decisions involve life-or-death consequences."

🔗 https://theconversation.com/ai-feels-like-an-unstoppable-force-but-it-is-not-a-panacea-for-businesses-or-society-242886

#ArtificialIntelligence #AI @ai

"i love big puffs, i can't deny..."

these guys were busy & bratty at the famous Owlet Lodge...

emerald-bellied puffleg

#hummingbird #hummingbirds #bird #birds #birding #photography #BirdPhotography #HummingbirdPhotography #NikonZ8 #Fotomontag #PhotoMonday

New haptic patch transmits complexity of touch to the skin https://www.eurekalert.org/news-releases/1063674 "Device delivers various sensations, including vibrations, pressure and twisting "; #haptics, sensory substitution

Bioelastic state recovery for haptic sensory substitution https://www.nature.com/articles/s41586-024-08155-9

🔴 AIs show a CV racial bias and absolutely no one is surprised

Mihai Andrei

"Across three million resume-job comparisons, resumes with white-associated names were favored by the AI models in 85% of cases. In contrast, resumes with black-associated names were selected only 8.6% of the time."

🔗 https://www.zmescience.com/other/economics/ai-racial-bias-cv/

#LLMS #AI #ArtificialIntelligence #Bias #Ethics #CV #Jobs #Race #Discrimination #Racism @ai

Childhood mortality -- death before age 15 or so -- used to run at about 50%.

Every second child born, died before becoming an adult, all over the world, for as far back as we've been able to track.

We didn't turn the corner until about 1900, when science got us the germ theory. That sparked sanitation and vaccination.

A cabinet nominee (RFK Jr) who questions vaccines is frightening. A nominee who brags about not washing his hands (Hegseth) is terrifying.

What does #neuroscience tell us about AI, and vice versa?

In this new PNAS paper, we find that real neurons' activation functions (f-I curves) share features with freq-used AI activation functions.

We measure many neurons w/ 2p holographic stim.

Work led by Paul LaFosse... 1/3 🧠📈 🧪

X is short for MAGA
https://eprints.qut.edu.au/253211/
Researchers find Twitter changed its algorithm to promote posts from Elon Musk and Republicans in the run-up to the election.

"The date at which (the spike) in engagement occurs coincides with Elon Musk's formal endorsement of Donald Trump on 13th July 2024."
#elonmusk #Election2024 #twitter #trump

I'm a neuroscientist who taught rats to drive − their joy suggests how anticipating fun can enrich human life https://theconversation.com/im-a-neuroscientist-who-taught-rats-to-drive-their-joy-suggests-how-anticipating-fun-can-enrich-human-life-239029 by @TheConversationUS; we likely need games for vision BCIs to make learning to see (again) more fun such that it is not only for diehards; #neuroscience

Very smol, very mindful.

As usual, Bernie speaks with absolute clarity on the disastrous performance of the Democratic Party ...

Documenting a prediction: This will receive an Ig Nobel in 2025.

Certainly is of the ilk of “achievements that first make people laugh, and then make them think.”

https://www.sciencedirect.com/science/article/pii/S2773186324001014?via%3Dihub

I can’t wait for in door navigation to be a real thing outside of only the largest cities. New apps will enable safer indoor navigation for blind people
https://www.htworld.co.uk/news/digital-health/new-apps-will-enable-safer-indoor-navigation-for-blind-people/

“Researchers say an AI-powered transcription tool used in hospitals invents things no one ever said - ABC News”

https://abcnews.go.com/US/wireStory/researchers-ai-powered-transcription-tool-hospitals-invents-things-115170291

The realities of evil academia

Anyone can learn #echolocation in just 10 weeks — And it remodels your brain https://www.scientificamerican.com/article/anyone-can-learn-echolocation-in-just-10-weeks-and-it-remodels-your-brain/ Now imagine what encoding a truly visual live camera view into sound may do to your brain, letting you hear zebra crossings and all things visual... #neuroscience

"Human echolocation repurposes parts of the brain's visual cortex for sound, even in sighted people."

AI in Epi 554 (part 1)

I offered students in Introduction To Epidemic Modeling For Infectious Diseases some general guidance on using AI this week, and I thought I'd share it more broadly. We are going to get into specifics for AI-assisted coding over the next few weeks, because that is one area where I think this stuff might really help them in this course. Introduction to Generative AI in Epi 554…

http://healthyalgorithms.com/2024/10/18/ai-in-epi-554-part-1/

The planet Venus passing across the face of the Sun captured by the Hinode spacecraft during a transit in 2012.

Venus's atmosphere is visible as a thin, glowing border in the upper left.

Credit: JAXA/NASA/Lockheed Martin