Functional identification of the zebrafish Interleukin-1 receptor in an embryonic model of Il-1β-induced systemic inflammation. https://www.frontiersin.org/articles/10.3389/fimmu.2022.1039161/full #Morpholino
An ancestral Wnt–Brachyury feedback loop in axial patterning and recruitment of mesoderm-determining target genes. https://www.nature.com/articles/s41559-022-01905-w #Morpholino
Elf3 deficiency during zebrafish development alters extracellular matrix organization and disrupts tissue morphogenesis. https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0276255 #Morpholino
NeuroD1 localizes to the presumptive ganglia and gut of the sea urchin larvae. https://www.micropublication.org/journals/biology/micropub-biology-000682 #Morpholino
Requirement of Zebrafish Adcy3a and Adcy5 in Melanosome Dispersion and Melanocyte Stripe Formation. https://www.mdpi.com/1422-0067/23/22/14182 #Morpholino
Elevated CD47 is a hallmark of dysfunctional aged muscle stem cells that can be targeted to augment regeneration. https://www.sciencedirect.com/science/article/abs/pii/S1934590922004271 #Morpholino
X-linked variations in SHROOM4 are implicated in congenital anomalies of the urinary tract and the anorectal, cardiovascular and central nervous systems. https://jmg.bmj.com/content/early/2022/11/15/jmg-2022-108738 #Morpholino
Zebrafish: A Tractable Model for Analysis of T Cell Development. In: Bosselut, R., Vacchio, M.S. (eds) T-Cell Development. https://link.springer.com/protocol/10.1007/978-1-0716-2740-2_22 #Morpholino
Dominant ARF3 variants disrupt Golgi integrity and cause a neurodevelopmental disorder recapitulated in zebrafish. https://www.nature.com/articles/s41467-022-34354-x #Morpholino
The circadian rhythm regulates branched-chain amino acids metabolism in fast muscle of Chinese perch (Siniperca chuatsi) during short-term fasting by Clock-KLF15-Bcat2 pathway. https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/circadian-rhythm-regulates-branchedchain-amino-acids-metabolism-in-fast-muscle-of-chinese-perch-siniperca-chuatsi-during-shortterm-fasting-by-clockklf15bcat2-pathway/6BEB93C5974C17ECB0A6355DE03996F3 Vivo-#Morpholino
A conserved megaprotein-based molecular bridge critical for lipid trafficking and cold resilience. https://www.nature.com/articles/s41467-022-34450-y #Morpholino
Planar polarized force propagation integrates cell behavior and tissue morphogenesis during convergent extension.
https://www.biorxiv.org/content/10.1101/2022.11.08.515701v1 #Morpholino
Syntaxin 4 is essential for hearing in human and zebrafish. https://academic.oup.com/hmg/advance-article-abstract/doi/10.1093/hmg/ddac257/6820909 #Morpholino
The apical ciliary adhesion complex is established at the basal foot of motile cilia and depends on the microtubule network. https://www.nature.com/articles/s41598-022-22871-0 #Morpholino
Acupuncture Needle-Based Transistor Neuroprobe for In Vivo Monitoring of Neurotransmitter. https://onlinelibrary.wiley.com/doi/10.1002/smll.202204142 #Morpholino as nucleic acid probe
osr1 Maintains Renal Progenitors and Regulates Podocyte Development by Promoting wnt2ba via the Antagonism of hand2. https://www.mdpi.com/2227-9059/10/11/2868 #Morpholino
Antibody-oligonucleotide conjugate achieves central nervous system delivery in animal models for spinal muscular atrophy. https://insight.jci.org/articles/view/154142 #Morpholino
Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR. https://www.nature.com/articles/s41467-022-34363-w #Morpholino
Awakening adult neural stem cells: NOX signalling as a positive regulator of quiescence to proliferation transition in the Xenopus retina. https://www.biorxiv.org/content/10.1101/2022.11.06.515333v1 #Morpholino
Mapping the convergence of genes for coronary artery disease onto endothelial cell programs. https://www.biorxiv.org/content/10.1101/2022.11.01.514606v1 #Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.