Transcriptome analysis reveals an Atoh1b-dependent gene set downstream of Dlx3b/4b during early inner ear development in zebrafish. https://journals.biologists.com/bio/article/12/6/bio059911/313578/Transcriptome-analysis-reveals-an-Atoh1b-dependent #Morpholino
Overlapping Targets of Shh and Gata3 during Craniofacial Development. https://www.researchsquare.com/article/rs-2973064/v1 #Morpholino
Role of maternal spiralian-specific homeobox gene SPILE-E in the specification of blastomeres along the animal-vegetal axis during the early cleavage stages of mollusks. https://onlinelibrary.wiley.com/doi/10.1111/dgd.12874 #Morpholino in Nipponacmea fuscoviridis (limpet)
Nsp14 of SARS-CoV-2 inhibits mRNA processing and nuclear export by targeting the nuclear cap-binding complex. https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkad483/7187708 #Morpholino
Calcium dynamics at the neural cell primary cilium regulate Hedgehog signaling-dependent neurogenesis in the embryonic neural tube. https://www.pnas.org/doi/10.1073/pnas.2220037120 #Morpholino
Development of a Gene and Nucleic Acid Delivery System for Skeletal Muscle Administration via Limb Perfusion Using Nanobubbles and Ultrasound. https://www.mdpi.com/1999-4923/15/6/1665 https://www.mdpi.com/1999-4923/15/6/1665 #Morpholino
Jak2 and Jaw Muscles Are Required for Buccopharyngeal Membrane Perforation during Mouth Development. https://www.mdpi.com/2221-3759/11/2/24 #Morpholino
Mitochondrial calcium signaling mediated transcriptional regulation of keratin filaments is a critical determinant of melanogenesis. https://www.biorxiv.org/content/10.1101/2023.05.26.542250v1 #Morpholino
Directionality of developing skeletal muscles is set by mechanical forces. https://www.nature.com/articles/s41467-023-38647-7 #Morpholino
Esrrγa regulates nephron and ciliary development by controlling prostaglandin synthesis. https://journals.biologists.com/dev/article/150/10/dev201411/310753/Esrr-a-regulates-nephron-and-ciliary-development #Morpholino
Genetic and protein interaction studies between the ciliary dyslexia candidate genes DYX1C1 and DCDC2. https://bmcmolcellbiol.biomedcentral.com/articles/10.1186/s12860-023-00483-4 #Morpholino
Inversin (NPHP2) and Vangl2 are required for normal zebrafish cloaca formation. https://www.sciencedirect.com/science/article/abs/pii/S0006291X23008136 #Morpholino
Etv5a suppresses neural progenitor cell proliferation by inhibiting sox2 transcription. https://www.liebertpub.com/doi/10.1089/scd.2023.0005 #Morpholino
Development and validation of a high throughput screening platform to enable target identification in skeletal muscle cells from Duchenne Muscular Dystrophy (DMD) patients. https://www.biorxiv.org/content/10.1101/2023.05.24.542079v1 Vivo-#Morpholino
A median fin derived from the lateral plate mesoderm and the origin of paired fins. https://www.nature.com/articles/s41586-023-06100-w #Morpholino
Cerebellar granular neuron progenitors exit their germinative niche via Barhl1 mediated silencing of T-Cell Factor transcriptional activity. https://www.biorxiv.org/content/10.1101/2023.05.25.542248v1 #Morpholino
Neural crest E-cadherin loss drives cleft lip/palate by epigenetic modulation via pro-inflammatory gene-environment interaction. https://www.nature.com/articles/s41467-023-38526-1 #Morpholino
Mutation of vsx genes in zebrafish highlights the robustness of the retinal specification network. https://elifesciences.org/articles/85594 #Morpholino
Identification of an α-l-iduronidase (IDUA) M1T mutation in a Chinese family with autosomal recessive mucopolysaccharidosis I. https://nyaspubs.onlinelibrary.wiley.com/doi/full/10.1111/nyas.15016 #Morpholino
DNAJB6 isoform specific knockdown: Therapeutic potential for limb girdle muscular dystrophy D1. https://www.cell.com/molecular-therapy-family/nucleic-acids/fulltext/S2162-2531(23)00135-X Vivo-#Morpholino
It's been all Morpholinos all the time for about 23 years. I'm a scientist with Gene Tools LLC.