kwitschas @kwitschas@qoto.org

Quite happy to share this latest work from our lab. In this study, we have addressed an important question of general importance: if and how brain medications (such as anti-depression drugs) change brain over time. We addressed this by specifically investigating the impact of an important drug, Ketamine.
https://www.biorxiv.org/content/10.1101/2023.04.12.536506v1
#biorxiv #neuroscience #ketamine #brainplasticity
thread ....

Are grid cells used for navigation? On local metrics, subjective space, and black holes @NeuroCellPress
https://www.sciencedirect.com/science/article/pii/S0896627323002234

Join us! We are searching for a #postdoc to join a cool #CellBiology project working on intracellular transport vesicles. #microscopy #imaging and pure discovery

https://www.nature.com/naturecareers/job/12797417/research-fellow-cell-biology-/

#vacancy #ScienceMastodon #WarwickUni

Machine learning can easily produce false positives when the test set is wrongly used. Just et al in
@NatureHumBehav suggested that ML can identify suicidal ideation extremely well from fMRI and we were skeptical. Today retraction and our analysis of what went wrong came out.

Here is the retracted paper: https://nature.com/articles/s41562-017-0234-y and here is our refutation https://nature.com/articles/s41562-023-01560-6. If true, the paper's approach could revolutionize psychiatric approaches to suicide.

So what went wrong? The authors apparently used the test data to select features. Obvious mistake. A reminder for everyone into ML: never use the test set for *anything* but testing. Only practical way to do so in medicine? Lock away the test set till algorithm is registered.

Side note: it took 3 years to go through the process of demonstrating that the paper went wrong. Journals need procedures to accelerate this. Also, all the good things of this were by
@tdverstynen

A reminder that SUNY Geneseo is hiring a #tenuretrack Asst Prof of #Biology in #plantscience #plantsci with interests in #sustainability and #global issues. Join our welcoming department that values #Diversity and #Inclusion and #UndergraduateResearch
We're a #PUI in western NY. Please share widely!

Details: jobs.geneseo.edu/postings/4254

#botany #Plant #vegetation #aquaticplants #MarshMadness #Forest #ForestEcology #nativeplants

My new group at Physics of Life, Technische Universität Dresden (@PoLDresden), is looking for an administrative assistant.

Join our wonderful admin team!
https://physics-of-life.tu-dresden.de/contact

Please apply here (in German)!
https://www.karriere.sachsen.de/karriere/stellenanzeige.jsp?q=Fremdsprachenassistenz&internalJobAdvertisement=&managerialResponsibility=false&searchRadius=25&fachbereichId=1&locationId=77&sortOrder=LATEST_RELEASE&page=1&id=27218

New posting! And a very personal one.

In January I handed in my resignation, and will be leaving the Department of Cell & Developmental Biology, the University of Würzburg, and the Physics of Parasitism network at the end of April.

I am #LeavingAcademia.

More discussion of this decision, the reasons for it, and what it means for TIR, in the posting below.

https://totalinternalreflectionblog.com/2023/03/19/changing-lanes/

Elliot Murphy ROSE: A Neurocomputational Architecture for Syntax https://arxiv.org/pdf/2303.08877.pdf

Strife at eLife: inside a journal’s quest to upend science publishing
Here's what's been going on w/
eLife and Mike Eisen: support and also some resistance - including editors' threats to resign.
Reporting by Alison Abbott | Nature
https://www.nature.com/articles/d41586-023-00831-6

Good opportunity and #great lab #postdocs #applynow
---
RT @DeNardoLabWUSM
Tumor Immunology postdoctoral position available!!
Are you interested in tumor immunology and/or the stroma? So are we! We are currently adding postdocs to our team. Visit website for details and email denardolabjobs@gmail.com
https://www.icce-wustl.org/david-denardo-lab.html
https://twitter.com/DeNardoLabWUSM/status/1636774382751334401

Further damage to the dysfunctional academic career system in Germany: The government has just presented its reform of the fixed term contract law (#WissZeitVG).
After years of #IchbinHanna protests, the max. length of fixed contracts for postdocs has been reduced to 3 years. The cynical argument: Careers become more predictable, because 3 years after your PhD, it's either professorship, third party funding, or exit.
The lack of a broader tenure track system makes this a devastating development.

“Opposition to eLife’s [publish everything, then review] model is driven fundamentally by powerful scientists not wanting to change a system that has benefited them and which they have sculpted to continue to reward them”.

Bingo.

https://www.nature.com/articles/d41586-023-00831-6