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Andrew Jones and Joshua Prince at Duke University developed a model that replicates #PeripherySequestration in #biofilms by accounting for heterogeneity of antibiotic attachment sites and porosity.
In the image we show how the heterogeneous distribution of the different matrix elements and the #bacteria themselves act as barrier against #antibiotics (in red), hindering their effect.
✏ Check out the paper at: https://www.pnas.org/doi/full/10.1073/pnas.2312995120
