Just published‼🎇
https://www.nature.com/articles/s41467-023-43737-7
We found contradictions in brain-wide associations of sleep 😴 and depression when participants were doing a task vs. resting state.
What does that mean❓❗

Resting-state brain dynamics were found to change sleep duration increase in a similar fashion as .... (wait for it)... insomnia frequency increase AND depression symptoms increase 🤨🤨
This was very robust observed in over 30k participants from
UK Biobank & Human Connectome Project.

Similarly, we found hyperconnectivity ⏫ associations of insomnia & depression in resting state but hypoconnectivity ⏬ in task
What does that all tell us ⁉

In insomnia and depression, resting-state dynamics are resembling those of rested-wakefulness... Your brain is giving you a signal that you don't need to sleep which looks like a hyperconnected state (hyperarousal?).

BUT in task connectivity drops which could be signifying a "local sleep" phase which decreases your cognitive performance as the brain is unable to recruit its resources to perform the task.