Dengue virus infected patients can generate false positives in the 'gold standard' Leptospira spp. microscopic agglutination test (MAT), immunofluorescence assays (IFAs) and immunoblot assays due to cross-reactive IgG and/or IgM antibodies against their outer surface membrane proteins https://www.medrxiv.org/content/10.1101/2023.03.13.23286524