What is going on with our immune cells after COVID-19 infection?
This thread will explore some of the impacts of COVID infection on our immune system even after people are recovered including:
- Missing naive T-cells
- Exhausted T-cells
- Loss of B-cell maturation
- Hyper-activated inflammatory response
- Immune system is impeded post-infection
- Immunological dysfunction persists 8+ months
- Depletion and dysfunction of dendritic cells
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Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants
https://www.cell.com/cell/fulltext/S0092-8674%2822%2901531-8
For subvariants BA 2.75.2, BQ.1.1, and XBB, in in vitro assays, bivalent boosting exceeds 1 or 2 monovalent boosting doses in neutralizing capacity.
Neutralization against BA.2.75.2, BQ.1.1, and XBB from mRNA Bivalent Booster
https://www.nejm.org/doi/full/10.1056/NEJMc2214293
Tracking the clonal dynamics of SARS-CoV-2-specific T cells in children and adults with mild/asymptomatic COVID-19
https://www.sciencedirect.com/science/article/pii/S152166162200290X?via%3Dihub#f0040
Systematic review of rhinovirus finds low evidence for fomite transmission and moderate evidence for airborne transmission. "This suggests that the major transmission route of RVs in many indoor settings is through the air (airborne transmission)."
https://www.sciencedirect.com/science/article/pii/S0196655322008665
The #WHO estimates of excess mortality associated with the #COVIDpandemic
Scientits estimate 14.83 million excess deaths globally, 2.74 times more deaths than the 5.42 million reported as due to #COVID19 for the period.
https://go.nature.com/3V9QNVn #OpenAccess
RT @SundermannAJ
Awesome to see @MackayIM's figure cited in @ICHEJournal 👏 https://twitter.com/ICHEJournal/status/1605633096157626373
Ten COVID Facts Health Officials Dangerously Downplay
Andrew Nikiforuk writes about 10 facts that everyone should know about but may not because public health has not educated people well enough ( https://thetyee.ca/Analysis/2022/12/21/Ten-Downplayed-COVID-Facts/ ). 🧵 1/
‘No ibuprofen, no aspirin, absolutely nothing’: China’s Covid patients feel the pain of drugs shortage
https://www.scmp.com/news/china/politics/article/3203742/no-ibuprofen-no-aspirin-absolutely-nothing-chinas-covid-patients-feel-pain-drugs-shortage
A MUST-READ
Elon's stale playbook. At Tesla and SpaceX, Elon Musk was a jerk with a grand vision. At Twitter, he's just a jerk.
El riesgo de contagio por #COVID19 en interiores fue 18,7 veces mayor que en exteriores, o lo que es lo mismo, un 5% de los casos ocurrirían al aire libre.
https://www.medrxiv.org/content/10.1101/2020.02.28.20029272v2
https://twitter.com/nauscopio/status/1604434587211399171
En respuesta a @Garcio72
[ Brote de Corea del Sur (no hay camellos) 1 enfermo provocó: 36/185=19,5%
Sea la mortalidad real diez veces inferior (muchos asintomáticos o no detectados), un 2% es el doble del SARS2 -> supongo que en población mayor / vulnerable será muchísimo mayor. ]
Lo que hay tras los rumores del “virus del camello” de Catar
https://www.farodevigo.es/sociedad/2022/12/18/hay-rumores-virus-camello-catar-80103065.html
Faro de Vigo: Rafa López - Lo que hay tras los rumores del “virus del camello” de Catar
https://www.farodevigo.es/sociedad/2022/12/18/hay-rumores-virus-camello-catar-80103065.html
Para celebrar mis primeros 30 días en #Mastodon, acabo de publicar esta guía rápida de iniciación a Mastodon para usuarios de #WordPress
Es un tutorial orientado a usuarios de WordPress pero que puede servir también a cualquier persona que esté migrando a esta plataforma.
Por favor, comparte
RT @LibDemPatrick@twitter.com
📢 FREE XMAS AIR FILTER! All the schools who wanted air filters in my area now have them ✅ Schools are now closed for Xmas so I’m giving away the left over air filters to families who need one at home. They’re no use sat in my garage unplugged!🔌 If you live nr #Yeovil DM me*
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🐦🔗: https://twitter.com/LibDemPatrick/status/1604078173385277440
Adding two blank spaces (before and after) to Mastodon's address, I was able to review it on Twitter:
A pocket-sized carbon dioxide logger and a spreadsheet is all that's needed to determine the #ventilation in a school portable classroom building after everyone leaves. #CovidCO2 #excel #spreadsheets #STEM