Rupert Overall @rupertoverall@qoto.org
- Website
- https://rupertoverall.net
I am a scientist researching the genetics behind brain ageing. My work includes phenomics (automated high-throughput behavioural phenotyping), systems genetics (multi-omics and quantitative trait locus mapping) as well as molecular pathway modelling (using disease maps, Boolean models and network analysis). All focussed on the question: how does neuron function change with age? #ageing #aging #genetics #genomics #systemsgenetics #qtl #lifespan #cognitive #healthspan #sbgn #openscience #behaviour #behavior #neuroscience
Joined Nov 2022
Rupert Overall
boosted
Very interesting #science news - the first SI prefixes since 1991 were announced today at the General Conference on Weights and Measures.
➡️ quetta = \( 10^{30}\), Q
➡️ ronna = \( 10^{27}\), R
➡️ ronto = \( 10^{-27}\), r
➡️ quecto = \( 10^{-30}\), q
For example the mass of an electron is just under one quectogram (1qg).
🔗 The resolution (in French) is available here https://www.bipm.org/documents/20126/64811223/Resolutions-2022.pdf/281f3160-fc56-3e63-dbf7-77b76500990f
We have written a piece describing how our new home-cage tracking paradigm can be applied to questions of behavioural individuality.
The manuscript is now online (#openaccess): https://doi.org/10.1016/j.nbd.2022.105916
Rupert Overall
boosted
RNAseq analysis of brain #aging in wild specimens of short-lived Turquoise #Killifish: commonalities and differences with aging under laboratory conditions
https://academic.oup.com/mbe/article/39/11/msac219/6759450?login=false
Rupert Overall
boosted
Upgrade your #causalinference arsenal.
A revision of our book "Causal Inference: What If" is now available
👇
https://hsph.harvard.edu/miguel-hernan/causal-inference-book/
Thanks to everyone who suggested improvements, reported typos, and proposed new citations and material.
Enjoy the #WhatIfBook.
Also, it's free.
Rupert Overall
boosted
Never thought Elon Musk would do so much for the adoption of a decentralised infrastructure…
Please Elon, can you buy Elsevier ?
Rupert Overall
boosted
There is tremendous risk in repeatedly analyzing data as it comes in…
For example, in the absence of any effect, the p-values of repeated t-tests on a growing dataset will randomly walk between 1 and 0!
Thanks to @lakens for inspiring this simulation!
Rupert Overall
boosted
As someone maintaining one of said affected CRAN packages - immensely grateful for everything Hadley & the tidyverse team do for the #rstats community
Making PRs to fix breaking changes in all of your reverse dependencies is a high, high bar to follow...
https://twitter.com/hadleywickham/status/1590455226569408512
Rupert Overall
boosted
In case someone didn't know, two books I've co-authored are freely available online for non-commercial use:
#Bayesian Data Analysis, 3rd ed (aka BDA3) at https://stat.columbia.edu/~gelman/book/ and lectures plus #rstats, #Python and #Stan code at https://avehtari.github.io/BDA_course_Aalto/
#Regression and Other Stories at https://avehtari.github.io/ROS-Examples/ including #rstats and #Stan code
The web sites also have links to the publishers' web stores if you prefer hard copies of these
Introducing my R package for the analysis of behavioural tracking data. Release version is focussed on the Morris water maze - but more to come.
Details, documentation and tutorials at the project website: https://rupertoverall.net/Rtrack/
- Website
- https://rupertoverall.net
I am a scientist researching the genetics behind brain ageing. My work includes phenomics (automated high-throughput behavioural phenotyping), systems genetics (multi-omics and quantitative trait locus mapping) as well as molecular pathway modelling (using disease maps, Boolean models and network analysis). All focussed on the question: how does neuron function change with age? #ageing #aging #genetics #genomics #systemsgenetics #qtl #lifespan #cognitive #healthspan #sbgn #openscience #behaviour #behavior #neuroscience
Joined Nov 2022
