Philipp Schlegel @uni_matrix@qoto.org

The #CampbellSiegert approximation is a method used in #ComputationalNeuroscience to estimate the #firingrate of a #neuron given a certain input. This approximation is particularly useful for analyzing the firing behavior of neurons that follow a leaky #IntegrateAndFire (#LIF) model or similar models under the influence of stochastic input currents. Here is a short #tutorial that introduces the concept in more detail:

🌍 https://www.fabriziomusacchio.com/blog/2024-09-04-campbell_siegert_approximation/

#CompNeuro #neuroscience #PythonTutorial

Our team is looking for an associate news editor with a background or strong interest in neuroscience, cognition and behavior, to write and edit news articles that educate, challenge and inspire our audience of neuroscientists. To apply, please visit: https://simonsfoundation.wd1.myworkdayjobs.com/en-US/simonsfoundationcareers/job/Associate-News-Editor_R0001667

🐣 New feature 🐣

The quick-select tool now works in 3D! Set the prediction depth and segment cells as before, now across multiple sections automatically.

Plus, you can now quick-select with just a click—no more drawing rectangles 🚀 Try it out now !

A great initiative to boost #OpenAccess academic journals. Basically, you pledge not to serve as peer reviewers for venues that do not make publicly available the research that we review. #NoFreeViewNoReview
Join us! Boosts are appreciated.
#academicchatter #academia
https://nofreeviewnoreview.org/

Modern science relies on (open source) software and hardware, but there is currently no incentive for researchers to provide feedback and improvement suggestions for tools that are use in the scientific community despite how valuable these contributions are to the scientific community as a whole. One possible way forward would be to treat "issue creation" and other Git-based activity as an acceptable form of peer review.

This is an issue and idea I’ve been thinking about for a while.I’d love to flesh it out into an actual set of actionable proposals/suggestions, as well as figuring out which (technological) hurdles would need to be overcome, in a opinion-styled paper - could anyone be interested in working on this together with me?

"Systematic annotation of a complete adult male Drosophila nerve cord connectome reveals principles of functional organisation" Elizabeth Marin et al. 2024
https://elifesciences.org/reviewed-preprints/97766

"This fundamental study provides a near-comprehensive anatomical description and annotation of neurons in a male Drosophila ventral nerve cord, based on large-scale circuit reconstruction from electron microscopy. This connectome resource will be of substantial interest to neuroscientists interested in sensorimotor control, neural development, and analysis of brain connectivity. However, although the evidence is extensive and compelling, the presentation of results in this very large manuscript lacks clarity and concision."

#Drosophila #neuroscience #connectomics #eLifeAssessment

Are you looking to become an assistant professor in Switzerland? This year you have two chances:
1- We've been re-admitted to the @ERC_Research starting grant program, deadline 15 Oct 2024 https://www.admin.ch/gov/en/start/documentation/media-releases.msg-id-101763.html
2- We still have @snsf_ch starting grants, deadline 15 Jan 2025
In both cases, consider @dee_unil as a host institution, we have excellent conditions and a beautiful campus! 😃
#ERC #StartingGrants

How the Tories pushed universities to the brink of disaster.

#UKPol no CW because #HigherEd

https://www.theguardian.com/politics/ng-interactive/2024/jul/02/how-the-tories-pushed-universities-to-the-brink-of-disaster

Presenting: Regexle, a wordle-like game for nerds 🤓

Guess the secret regular expression by testing strings against it!

@piko and I might be two years late with this project, but here we go!

https://regexle.ithea.de

Our preprint "Connectome-driven neural inventory of a complete visual system" (Nern et al., 2024) was published on bioRxiv today https://doi.org/10.1101/2024.04.16.589741. We are looking forward to your feedback on this #Drosophila #neuroscience #prePrint.

In this short thread, I also wanted to highlight a few more resources that we published at the same time. 1/5

Octarine

A new lightweight, WGPU-based 3D viewer for Python.

https://github.com/schlegelp/octarine

You don’t become cooler with age, but you do care progressively less about being cool, which is the only true way of being cool. This is called the Geezer’s Paradox

The Janelia #Unity Toolkit now supports panoramas, back-projected onto a cylindrical screen, updated in real time for a tracked viewpoint within the cylinder. The intended application is #VR for #Neuroscience studies of animals like #Drosophila. The code is a byproduct of another project so it's a bit experimental, but it's fun to watch examples like this one, meant to be displayed with three adjoining projectors. (1/2)

https://github.com/JaneliaSciComp/janelia-unity-toolkit

Update: Elon Musk has announced he’s reinstating the Twitter/X account of far-right conspiracy theorist Alex Jones.

How QR codes are made:

Loren Looger, legendary protein wrangler, who always generously shared their genetically encoded calcium indicators and more while still in development and unpublished, is asking for labs to co-write grants with him:

"Dear science world, I need help, please. If you like the tools and data we generate, and our shareware attitude, can you please co-apply for funding with us? It turns out that I'm terrible at writing grants, and we need $$ or else we can't make more GCaMPs, RCaMPs, SnFRs (we've branched out to neuromodulators and neuropeptides), FPs, viruses, tags, etc. We'll also make whatever you want, but we need $$ to do it. DM or email me, sooner is better. Sorry to be desperate, but we want to keep doing this, and I'm not sure we can."

https://profiles.ucsd.edu/loren.looger

#neuroscience #GCaMP #RCaMP #SnFR #ProteinEngineering #GECIs