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TDK introduced a 1uF, 100V capacitance in an EIA 0603-sized case. The press release suggests it targets 48V systems (like data centers.) At 50V, the effective capacitance isn't even 200 nF.
https://product.tdk.com/en/search/capacitor/ceramic/mlcc/info?part_no=C1608X7R2A105K080AC
That DC bias effect is real.
@baldengineer Yeah I'm using a 10 uF TDK on the input to my 48V DC-DC converter https://product.tdk.com/en/search/capacitor/ceramic/mlcc/info?part_no=CKG57KX7S2A106M335JJ
along with a pair of 100 uF bulk aluminum polymer hybrid https://na.industrial.panasonic.com/products/capacitors/polymer-capacitors/lineup/polymer-hybrid-aluminum-electrolytic-capacitor/series/142648/model/142850
The TDK is a 2220 package with a max 100V rating, and is still about 4 uF at 48V. But that's vastly bulkier than an 0603.