"In the hippocampus, the activation of microglia was associated with inhibited neurogenesis, which could explain impaired memory formation in patients. The activation of microglia appeared to be mediated by persistently elevated levels of a molecule called C-C motif chemokine 11 (CCL11). CCL11 has been associated with aging and with inhibition of neurogenesis."
https://www.nejm.org/doi/full/10.1056/NEJMcibr2210069?query=featured_home