Clinical studies suggest that patients treated with the new class of weight- loss drugs, known as GLP-1s, lose muscle at far faster rates than people losing weight from diet or exercise, exposing them to health problems, said George Yancopoulos, who also serves as Regeneron’s chief scientific officer.
ft.com/content/094cbf1f-c5a8-4

Israel's attacks on Lebanon have killed 2000 and displaced over a million now.

Here's another aspect of the story you're not likely to have heard of: Lebanon's African migrant community, which numbers around half a million, are among the displaced, the fleeing, the injured.

Unfortunately, and this is incredibly heartbreaking to say it, African migrants are being denied space at shelters that are being declared "Lebanese only."

@blogdiva I purchased multiple copies of her autobiography “Breaking Through: My Life in Science” as soon as it was rea released and gave them to friends and relatives as gifts. It is a wonderful read.

penguinrandomhouse.com/books/7

'Springer Nature shares gained 8.2 per cent to close at €24.24 in Frankfurt, having priced the stock in the IPO around the middle of its targeted range at €22.50. The rise valued Springer, which sold €600mn of shares as part of the deal, at €4.8bn.'

ft.com/content/6905d256-787b-4

ancient DNA is so cool.

'We found this weird bone of a species we thought had no earthly business being there?? and here is it's assembled mitogenome proving it to be a distant relative of currently living species'

onlinelibrary.wiley.com/doi/fu

'In this work, we developed a mRNA–LNP vaccine targeting C. difficile toxins & virulence factors. This multivalent vaccine elicited robust and long-lived systemic & mucosal antigen-specific humoral and cellular immune responses across animal models, independent of changes to the intestinal microbiota.'

science.org/doi/10.1126/scienc

There's long been one mantra in mainstream economics: Growth is good. But recently, an alternative term has begun taking root in popular culture and policy: "degrowth." japantimes.co.jp/business/2024 #business #economy #globaleconomy #koheisaito #universityoftokyo

This is really good ⬇️
LYCHOS is a human hybrid of a plant-like PIN transporter and a GPCR | Nature
nature.com/articles/s41586-024

'In a panic, I asked a graduate student in my lab for help. We defined a goal for the paper, and I carefully wrote an outline. But when I asked him for feedback, I soon found the paper covered in red marks. Not again.

Before I could retreat in defeat, though, the graduate student explained that red didn’t mean I was a bad writer. Writing isn’t a one-and-done thing. It requires revising your work, often several times. Suddenly it occurred to me, “Hadn’t I done the same thing when I was searching for an efficient inductor design?”'

science.org/content/article/i-

'O teste aprovado pela OMS – o Alinity mMPXV fabricado pelos laboratórios Abbott Molecular – é um teste PCR em tempo real que pode detectar o ADN do vírus, tanto da variante 1 como da variante 2, a partir de esfregaços de lesões cutâneas humana.'

publico.pt/2024/10/04/ciencia/

'To his credit, Jones does not back away. His narrative of Henry’s life is a chronicle of coldhearted decisions, of sieges and massacres, of close friends executed for their real or perceived disloyalty, of heretics burned at the stake, of a damaged soul incapable of gentleness or love. This was Shakespeare’s problem as well, and it is an artistic miracle that the playwright managed to acknowledge much of what was truly awful about Henry without alienating the audience from him. Instead, his play brings the audience ever closer to what was transpiring inside the lonely young king.'
nytimes.com/2024/10/04/books/r

#OtD 5 Oct 1839 French bookbinder and son of an agricultural labourer, Eugène Varlin, was born. An organiser in the Bookbinders' Society, he became a socialist and member of the First International. He died during the Paris Commune stories.workingclasshistory.co

#IDMastodon #Immunology #Inflammasomes are multi-protein complexes that assemble within the cytoplasm of mammalian cells in response to pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs), driving the secretion of the pro-inflammatory cytokines IL-1β and IL-18 & pyroptosis. This #Clinicalreview on the Molecular mechanisms of emerging inflammasome complexes & their activation signaling in inflammation & pyroptosis

I was in Beirut 2 years ago and it was one of my favorite cities to visit. Absolutely insane seeing Israel blowing it up. Have now heard from a friend who fled from Lebanon to Syria for safety. Can you imagine this? Fleeing to Syria? 😔

📢Do you work in #DevBio and #StemCell biology? Do you want to gain more #SciComm experience?

The Node is looking for a reporter for @Co_Biologists Biologists @ 100 conference! #biologists100

📅24-27 Mar 2025
📍Liverpool, UK

Find out more and apply now:
thenode.biologists.com/apply-t

Zacharias stood watch behind the door.
Léon Benett, from "Contes et romans populaires" by Émile Erckmann & Alexandre Chatrian, Paris: n.d. #illustration #art oldbookillustrations.com/illus

#OtD 4 Oct 1936 the Battle of Cable St took place when Oswald Mosley's British Union of Fascists tried to march through East London. They were met by over 100k local workers who fought the blackshirts and the police protecting them, stopping the march workingclasshistory.com/2020/0

Cytomegalovirus Restricts the Innate Immune Response by Nuclear Export of Host Restriction Factor DDX41 biorxiv.org/content/10.1101/20

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