'During the current outbreak of #monkeypox (recently renamed mpox), #smallpox #vaccination has been recommended to prevent mpox infection in persons who have had mpox exposure, but evidence to support this practice is limited.1,2 We conducted a study to evaluate potential breakthrough infections in participants who had received smallpox vaccine after high-risk exposure to mpox.'
Gathering real world data on the efficacy of drugs and vaccines used to treat or prevent #monkeypox is vital. Many where developed for #smallpox and approved via the FDA's "animal rule", which means that although the safety data is there, the efficacy is essentially unknown. I wrote a bit about this for #NatureMedicine in September when looking at the use of the #antiviral #tecovirimat for monkeypox.
@cyrilpedia great work Thiago, thanx for sharing
