'However, beyond emergence, there is little information regarding whether developing HSCs respond in utero to maternal inflammation, how they respond, and the consequences for postnatal hematopoietic and immune development. We hypothesize that the fetal HSC response to prenatal inflammation drives lasting changes to hematopoietic output in offspring that shapes the postnatal immune response.'
https://www.cell.com/cell-reports/fulltext/S2211-1247(22)01551-0