My new Clinical Pipeline column is out in Nature Medicine.
It's on JAK inhibitors for alopecia - and at the black box safety warning the FDA attached to this entire class of drugs.
#Immunology #drugdiscovery #drugdevelopment #alopecia
@cyrilpedia nice piece, and also informative. Had missed the black box warning on the whole JAK Stat family! Is the increased cardiovascular risk dose / time dependent, or is it idiosyncratic?
@gpollara I don't think we have enough data on that - the group that generated the warning (in another trial set) was oder and had a range of pre-existing conditions.
