"Our experiments confirm that GCs support the side-by-side maturation of B cells with very different BCR affinities and reveal that cells from across a wide antibody affinity spectrum generate PCs. We propose that this outcome reflects imprecise discrimination for antibody affinity by GC B cells in such settings, with the result being PC populations that approximately mirror the maturation pathways from which they develop. This provides the evolutionary benefit of seeding diverse serum antibody responses."
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https://www.cell.com/cell/fulltext/S0092-8674(23)01173-X#%20