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"Our findings expand on previous work measuring genetic ancestry effects on the gene expression response to pathogens or immune stimuli by showing that many of the ancestry-associated differences in transcriptional responses to pathogens are accompanied by epigenetic differences between ancestry groups. More generally, our data help fill a critical gap in biomedical research: the limited number of non-European ancestry individuals among cohorts designed to study immune variance in the general population and in genomic studies more generally."
#Immunology #Epigenetics
