'Our results reveal an increased sensitivity of low affinity CAR-T cells to PD-L1-mediated inhibition when compared to their high affinity counterparts by using in vitro models of tumor cell lines and supported lipid bilayers modified to display varying PD-L1 densities.'
#Immunology #Immunotherapy #CARTcells
https://www.nature.com/articles/s41467-024-47799-z