'However, whether Treg cells hamper pain at steady state and by which mechanism is still unclear. From a meta-analysis of the transcriptomes of murine Treg and conventional T cells (Tconv), we observe that the proenkephalin gene (Penk), encoding the precursor of analgesic opioid peptides, ranks among the top 25 genes most enriched in Treg cells.'
#Immunology #Preprint #Neuroimmunology #Treg
https://www.biorxiv.org/content/10.1101/2023.09.12.557326v2