'A larger number of S. aureus macrophage pathogenesis genes (n = 27) are newly implicated by this effort, comprising 61% of genes passing experimental validation. The putative or documented roles of many mirror the functions of known virulence factors (…) However, other newly validated genes offer insight into previously unappreciated mechanisms affecting intracellular macrophage pathogenesis. The most substantial constellation of functionally related genes include fmhA [99], femA [100], femB [100], and pbp2 [100], all of which have functions in peptidoglycan assembly.'

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1012394