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"But apart from the permanently central role of technology in microbiology, there is one conceptual fracture in our otherwise continuous progress toward a better understanding of microbial life that can serve as a line between the still alive and well classical roots of microbiology and its aspiring modern times: our expanding focus from individual organisms in cultures to complex communities in natural habitats, with the admission that “a pure culture is not enough."

cell.com/cell/fulltext/S0092-8

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