As a mature adult, is a bad cycle of sleeping poorly impacting your cognitive function?
> Dr. Lim, an associate professor of neurology at the University of Toronto ... suggest[s] microglia play a role in the link between poor sleep and cognitive impairment and dementia. Microglia normally help fight infections and clear debris from the brain. But dysfunction of microglia appears to be involved in the development of Alzheimer’s disease, Dr. Lim said. [....[
> Dr. Liu-Ambrose, the Canada research chair in physical activity, mobility and cognitive neuroscience at UBC, said good-quality sleep is believed to allow the brain to clear itself of toxic beta-amyloid protein, the buildup of which is one of the characteristics of Alzheimer’s disease. And, she said, there is also good evidence to suggest an accumulation of beta-amyloid can further contribute to disrupted sleep.
> “It’s a vicious cycle,” she said.
"Study finds link between dementia and lack of sleep" | Wendy Leung | Dec. 11, 2019 | Globe and Mail at https://www.theglobeandmail.com/canada/article-study-finds-link-between-dementia-and-lack-of-sleep/
The scientific publication is:
"Sleep fragmentation, microglial aging, and cognitive impairment in adults with and without Alzheimer’s dementia" | Science Advances | Dec. 2019 at https://advances.sciencemag.org/content/5/12/eaax7331 doi:10.1126/sciadv.aax7331
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