If we use the time-mediated pseudocausal influence loop definition of reality, then your own nonphysical qualia informationspace is real iff its time evolution operator exists
By time-mediated map loop I mean some composition of maps between objects that start and end at the same place though not necessarily at the same time. And these are pseudocausal maps, which point in the direction of pseudocausal influences. Pseudo- because causal influences probably actually only go one way (meaning with no reverse causality: two things cannot mutually cause eachother), but changes in one thing (eg: your brain) might causally influence another thing (eg: your mind) in a way that looks like its the other direction (eg: your mind moves your arm)
So for instance, for a physical process P, another physical process Q is real from P's perspective iff there is a pci map G from P to Q and a pci map H back to P from Q such that for P's time evolution operator Tp and Q's time evolution operator Tq that H Tq G P = Tp P. Note that this composition (H G) takes P back to itself (its an identity), but the composition conjugated with Q's time operator (H Tq G) takes P back to itself at a different point in time (H Tq G = Tp). Q is real from P's perspective because of this loop
For your own qualia informationspace u with time operator t and the physical process causally simulating it P with time operator T, there is a pci map e to u from P and inverse h to P from u. From *your* perspective P is real since e T h u = t u. And the identity function Iu for u can form a trivial loop with t: Iu^-1 t Iu = t, so u is always real granted it has a time evolution operator. Of course, if you have no time evolution operator then you're kind of fucked anyway
I think I'd categorize this idea as not-useful for a variety of reasons. But it could probably be made useful (well, maybe not useful, but consequential or at least implicative) if you tweaked some assumptions. For instance if you assume all pseudo-causal influences are actually causal, that would leads to some crazy shit let me tell you hwhat