My workflow is such that I like to keep manual profiles to isolate different use cases for the browser, but firefox profiles are too cumbersome to switch between, and Multi-Account containers just don't work well for me, so I end up with Firefox as my "open any link" browser, and Chrome as my "different profile for each different service" browser (e.g. twitter has one profile, github has another, and LinkedIn is always in incognito windows on a dedicated "clear everything" profile — and even then I think to myself I should probably only be accessing that website via Qubes OS or something).