RE: biologists.social/@flypapers/1

Finally the connectome of the adult fly brain (#Drosophila #FAFB) has been split into axons and dendrites.

Let's see if all the graph theoretic labs and computational neuroscience labs stop modeling the fly brain with single-compartment models.

#neuroscience

@albertcardona

I'd be a bit cautious about these for now. As far as I can tell they did no quality control on the A/D splits and in my experience the algorithm can get around 30% wrong (or at least not entirely right) due to issues with skeletons, synapse detection/segmentation or genuinely odd neurons. Something to address in the review, I suppose.

PS: Alex also made A/D splits for the BANC!

@uni_matrix

Indeed, very happy that Alex Bates did the splits for thr BANC. I am exhausted from the never-ending stream of just-so graph theoretic analyses of the single-compartment FAFB connectome.

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@albertcardona

We just had this discussion internally - not with respect to single compartments but rather a recent slew of half-baked connectome analysis papers that many of us were asked to/had to review. Birthing pains of an expanding field?

@uni_matrix

Rather, opportunistic “I hold a hammer and everything looks like a nail” sort of papers. Desk-rejected so many, most didn’t even make an effort to pretend to be explaining something about brain structure or function.

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