Caroline Bartman @Caroline_Bartma@qoto.org

Re-posting an #introduction after moving server:

My research group at the Wellcome Centre for Human Genetics in Oxford uses #SingleCell techniques and Genome Architecture Mapping to study #epigenetics #Chromatin and #GenomeFolding in rare #NeurodevelopmentalDisorders.

I (He/Him) love to be outside #Hiking or #Cycling and I’m a big fan of #FlightFree travel. Interested in #Equity issues in STEM, trying to read and educate myself to be a better ally.

Toot at me with your #Andor theories!

If you have cell counting fatigue and don't have a fancy and pricey automated cell counter, check it out! /x

Android: https://play.google.com/store/apps/details?id=com.NicholasBauer.HemocytometerSidekick.XF

iOS: https://apps.apple.com/us/app/hemocytometer-sidekick/id1341492266

#hemocytometer #cellcounting #biology #science #apps #microsoft #maui #xamarin #android #ios

'Immune response to the vaccine mRNA is the most literal example of “killing the messenger” that I can think of, short of the Spartan treatment of Darius’ envoys in 491 BC.'
cc @Caroline_Bartma
https://www.science.org/content/blog-post/curevac-comes-around

I'll admit to being skeptical about "synthetic biology", wondering if it's just buzz words, but this recent paper from Daniels et al. blew me away with its combination of novel insights into cell signaling circuitry & its clinical potential 1/n
https://pubmed.ncbi.nlm.nih.gov/36480602/

One central question has motivated me for the last 10 years: how are immune responses to parasitic worms and allergens initiated?

Here Margaret McDaniel and I got to review some of the relevant literature and share our thoughts. Also check out original figures (artwork really) by Heber Lara.

https://www.mucosalimmunology.org/article/S1933-0219(22)01181-3/fulltext

Took 1-8y off science for family during your postdoc or faculty position?

Contact NIH-funded labs to see if they will write a reentry for you (I will!). Please boost these little-known supplements:

https://www.nigms.nih.gov/Research/Mechanisms/Pages/PromoteReentry.aspx

#FamilyLeave #ResearchFunding #STEM #Fellowship #Grant

“Forget inspiration. Habit is more dependable. Habit will sustain you whether you’re inspired or not. Habit will help you finish and polish your stories. Inspiration won’t. Habit is persistence in practice.” — Octavia Butler

#writinglife #writingcommunity #writerscommunity #creativity #inspiration #writing #storytelling #screenwriting #writingtips #art #OctaviaButler

The latest episode of the #EMBOPodcast is out.

I spoke with Steve Quake, the new head of science at CZI (taking over from @CoriBargmann) about his career, #OpenScience, cell atlases, imaging, @ReviewCommons and lots more.

You can listen to it at the link below or on any podcast app.

#SciencePodcast #SciComm

https://www.embo.org/podcasts/the-biologists-were-pretty-darn-good-with-their-microscopes/

Awestruck by this map of submarine telecom cables.

I found it when my kids asked me whether the internet works entirely through radio waves and satellites because of how we connect to it via Wifi (typically). A fair question, I thought.

I mean, did you know that there are around *1.4 million kms* of cables criss-crossing the seas and oceans of the world?!

Happy to see our News & Views published in Nature Chemistry, written with postdoc in the lab Chris Watkins, about two new papers from Lei Wang’s @UCSF on their sulfur(vi) fluoride exchange (SuFEx)-based chemical crosslinking methods – useful for RNA-protein and glycan-protein interactions!

https://doi.org/10.1038/s41557-022-01116-7

Our first editorial of the year, with
Jake Yeston and Valda Vinson, includes two big announcements: the end of Reports in Science and an additional criterion for retractions when editors have lost confidence in a paper. https://www.science.org/doi/10.1126/science.adg4111

Life as an academic scientist would be infinitely better if there were hard money permanent positions for technicians and programmers.