Markus Sommer #biodata22 closing us out with "Structure‐guided isoform analysis for the human transcriptome".
Problem: We have many more transcript annotations than genes. Which isoforms actually represent functional proteins?
Leveraging folding algorithms (e.g. AlphaFold2) to score each isoform, high score = more likely to be functional. Showed some examples where this scoring approach matches experimental data. Says not perfect, but helpful data point.
Website: https://www.isoform.io/
RT @Rainmaker1973@twitter.com
Where the terms 'uppercase' and 'lowercase' came from: from the early days of the printing press
[read more: https://buff.ly/2J5iUB6]
🐦🔗: https://twitter.com/Rainmaker1973/status/1591415327887609856
So I'll start as I'd like to think I'll go on - with a photo! And I'll start with a good one! It's not new, but hey, you've probably not seen it before 😂
#Peebles in the Scottish Borders at sunset, a January a few years ago
It was spectacular! And pure luck that the photo wasn't ruined by camera shake as I was shooting over a 6 foot wall!
@StephenSenn The defender of GenStat and the destroyer of the Number Needed to Vaccinate numpties is here.
@lakens @Andi @AndrewPGrieve @mike_johansen
@doctoroxford welcome aboard a far nicer ship
https://t.me/liveukraine_eng/804 ⚡️🇺🇦 President Zelensky: Today is a historic day. We are regaining Kherson. As of now, our defenders are approaching the city. But special units are already in the city. The people of Kherson were waiting. They never gave up on Ukraine. Hope for Ukraine is always justified – and Ukraine always regains its own. And even when the city is not yet completely (VIDEO and more) #Ukraine #News #War #Russia
@tripe hashtags very useful here from #Tripe to #SirNorman
Biological Chemist. Blog https://ferniglab.wordpress.com
#Polysaccharides, #ExtracellularMatrix, fibroblast growth factors, #FGF, #Glycotechnology, #Sulfation.