MRTF-A as a deacetylation target of Sirt6 in #EndothelialCell
Deactylated MRTF-A stays in cytoplasm, failing to mediate oxLDL-induced EC ICAM1
An OxLDL-DNMT1 cacade epigenetically silences Sirt6 expression
Dr. Qianyun Wang, Tianfa Li & Qianwen Zhao labs Cell Death Discov 2022
https://www.nature.com/articles/s41420-022-00903-y