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A mind-blowing paper from Dr. Bin Zhou lab🤯
Genetically Labeling/Tracing Cell Contact events & post-contact consequences
Tigre-SynNotch + Cre & Dre tri-transgenic🐭
One can track Ongoing+History of Contact (likely minimal 2-h) b/w any 2 cell types
Embryonic Cardiac #EndothelialCell not only constitutes 20% of Liver vessels but also colonizes Skeletal muscle (~5% Fig S11B)
How will this contact tracking system revolutionize our research?😄
Dendritic cell-> atherogenic SMC?
Senescent pericyte->Capillary shear sensing?
