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Surgery or Endovascular Therapy for

A good-quality great saphenous vein for conduit+
Surgery-first->
32%⏬risk of MALE/Death vs endovascular strategy

Dr. Alik Farber, Matthew Menard, et al BEST_CLI NEJM 2022
nejm.org/doi/10.1056/NEJMoa220

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Our most recent #preprint (biorxiv.org/content/10.1101/20) was submitted for peer review by eLife under 'the new model' - I'm happy to share that it is now undergoing in-depth peer review. To celebrate, here's a cell that's making a little dance, guided by light
#OptoGenetics

Mst1 KO->
⏫EC inflammation by 0.5±4 dyn/cm2 1 Hz
⏫🐭

Independent of (?TAZ🧐)

Mst1 phosphorylates ->⏬Hemichannel activity, not gap junction coupling

Dr. Ding Ai lab Circ Res 2022
ahajournals.org/doi/full/10.11

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RT @TonyZador@twitter.com

We used BARseq in situ sequencing to identify genes in ***1.2 million neurons*** throughout the mouse brain

We found that cortical areas with similar cell types are also interconnected. We call this “wire-by-similarity.”

biorxiv.org/content/10.1101/20
1/n

🐦🔗: twitter.com/TonyZador/status/1

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Watch this and try not to think about the space.
Congratulations @DInoueMT 💪🏼
---
RT @DInoueMT
After reading the paper, you will get some idea to understand why two different types of chiral patterns, i.e. monopolar rotational spiral and bipolar nematic pattern, emerge from gliding microtubules.
twitter.com/DInoueMT/status/15

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A few tips for newcomers, as I have learned myself in the past week...

#AltText Descriptions: Please use them, many folks here depend upon them and have been using them for years before we all arrived.

#CamelCase: when you use hashtags, use Camel Case if you have more than one word: #WelcomeToMastodon is easier to read than #welcometomastodon - so do that. Use WAAAAY more hashtags than you are used to on Twitter. Mastodon is hashtag dependent.

#ContentWarning: If you are posting something that might even in the slightest trigger another person, use the Content Warning (CW) option that you can toggle on at the bottom of the toot window. It's polite here. People can choose how they want to view and interact. Use CW more than you are used to on Twitter.

#Diversity: a few people have commented, "lots of white men here!" Well, ok, but you can also find each other by using hashtags like #WomenInStem #BlackMastodon and many more including my favorites that I started up: #Desi and #MixedDesi (i.e. me). Start your own if you don't see yourself represented, so others can find you, too.

#DMs: are under the globe option in the toot window for privacy setting and they appear in your full list / feed of notifications (don't freak out at that).

#Donations: This is all run by volunteers. Make a donation. Click on the "about this server" at the bottom of your screen (might appear in a different location than on mine) and find out who is running your server and how to make a donation. And thank them!

#Introductions: Please write a friendly intro and use the hashtag #introduction so people can learn about you. Be interested in others. Grow your community through daily, friendly interaction.

Have fun! This is like a big global cafe with many tables to sit at, and conversations to be had.

Lots more tips linked in my feed. Welcome!

Hao Yin boosted

Great to witness activity building here. Will hang on to any hope on a day like today. Hope everyone is voting!

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Americans - Please vote today 🙏

Especially young people.
Remind your family and friends to vote.
Please. Everything is at stake.

Hao Yin boosted

Hey everyone !

Time for my #science #introduction

I am the PI of the @cellcommlab @ the UKE in Hamburg, Germany. We use #microscopy & #imageanalysis to study how cells move & communicate.

I am from #Chile, where I did my #PhD at PUC, then moved to Paris to work at the Institut Curie and IPGG.

After quite some years in #science (20 since I started my BSc !) I keep my fascination to observe how cells do things, like these migrating leukocytes.

#scicomm #sciencemastodon #nomoa

Arterial dictation of fetal 👹

Fetal bone marrow Bmx+ arterial (not Myh11+ mural cell) Wnt2->
⏫c-Kit+ HSPC β-catenin signals->
⏫colonization & transplant engraftment

Dr. Ralf Adams lab Nature Commmnications 2022
nature.com/articles/s41467-022

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We really need a #DevBio hashtag to bring us all together here.

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Hi All! Happy to be here - this is my #introduction. I'm an assistant professor at the University of Amsterdam and we are creating and applying fluorescent probes for imaging of cells with microscopes.
I'm also interested in image analysis and #dataViz with #opensource tools.

Hello, I am a postdoctoral research associate at Robarts Research Institute, Canada.

I have been studying vascular biology, with a specialized focus on Aorta & muscle microvasculature, and broad interests in biomedical & biological sciences.

Currently writing up all viable projects in my generation Hopefully to be on the job market soon.

Nice to meet everyone on Mastodon

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Hi #ScienceMastodon
I’m a professor of molecular biology at UT Sorhwestern Medical Center. Our lab works on organ development, with a focus on the cardiovascular system, pancreas, kidney and lung. We use mouse models and organoids to ask questions about cell fate. Looking forward to learning and interacting here, as on Twiiter (let’s see how that site develops with the “change in leadership”).

Hao Yin boosted

Quick question: can we be on multiple servers? Lots of peeps I don’t see because they are on “different servers”. Still getting used to this place…

Hao Yin boosted

You all are awesome for trying to explain Mastodon to me 💙 but it’s gonna take me a while 😂 (also, why can’t I attach images?) twitter.com/cstegman/status/15

proteolysis-targeting antibody
An evolving variant

Use tumor-enriched cell surface RNF43/ZNRF3 for targeted degradation of transmembrane proteins IGF1R/HER2/PD-L1

Dr. N. Agard & F. de Sousa e Melo labs @Nature 2022 @genentech
nature.com/articles/s41586-022

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