Combinatorial interpretation of BMP and WNT allows BMP to act as a morphogen in time but not in concentration. 

"[...] varying the duration of leads to either pluripotent, mesodermal, and extraembryonic states, while varying the concentration does not cause efficient mesodermal differentiation at any dose [...] appropriately timed pulse of BMP induces to a mesodermal fate more efficiently that sustained signaling at any concentration. [...] this effect is due to a combinatorial interpretation of the applied BMP signal and induced endogenous signaling."

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