>It is the self-organizing and self-assembling properties of *inanimate* molecules that make the origin problem much less difficult. The mystery probably does not have a complete solution, but amazing partial solutions have been discovered in my lifetime. Most promising are:
(1) the rich *abiogenic* syntheses of amino acids, nucleobases, and many other biomolecules, and
(2) the *spontaneous* folding and assembly of linear copolymers of amino acids and nucleotides to form enzymes and higher order molecular structures.
>The origin of the genetic code and genetic language is still the greatest mystery, but whatever the answer, it is a fact that for over 4 billion years of evolution linear copolymer folding has remained the essential symbol grounding process that enables *1-dimensional genetic symbolic descriptions* to construct and control the *3-dimensional molecular machinery of all life*. These folded macromolecules also have remained as the *initial detectors of sensory information* at all levels of evolution. Any biosemiotic studies should understand these universal ***molecular symbol-matter and matter-symbol transitions***.
https://www.academia.edu/44551141/The_Primary_Biosemiosis_Symbol_Sequence_Grounding_by_Folding