Shai Bel @Mucus_Man@qoto.org

We preprinted a revised version of work by Carrie Zhu and colleagues, taking a new approach to understand sex differences in genetic effects on complex traits. Below are some of the revision highlights.

https://www.biorxiv.org/content/10.1101/2022.05.06.490973v1

Happy to have joined Mastodon!

If you're getting a manuscript final ready for the end of the year, my advice is: don't submit it to a journal now, it will only create frustration as editors and reviewers take holidays while journals are submerged with "managed to finish in 2022" manuscripts. Rather, preprint it now, and submit mid January, with the benefit of feedback and time to think, and editors and reviewers now slightly more available. #preprint #protip

#IDMastodon Nasal flu vaccine may help reduce cases of group A strep
Analysis by @UKHSA suggests a nasal spray vaccine that offers protection to children against flu may also help reduce the rate of group A strep infections.
https://www.gov.uk/government/news/nasal-flu-vaccine-may-help-reduce-cases-of-group-a-strep
https://khub.net/documents/135939561/174090236/Impact+of+the+paediatric+LAIV+programme+on+Group+A+Streptococcus+infections.pdf/99908afc-27ef-526e-0a9a-ab802c1bce14?t=1671204658432

Clouds that lour'd upon Alamada

New #instance , new #introduction !

I am a neuroscientist based in sunny Marseille (France).

After a PhD in NYC in the lab of JL Pena, and a postdoc with Zach Mainen and the #InternationalBrainLab, I recently joined the #CNRS as a tenured researcher.

My work combines #experimental and #computational approaches to study the neural dynamics of flexible behavior in mice. My research is supported by the Simons Collaboration on the Global Brain (#SCGB).

#neuroscience

Here is my first attempt of a thread, presenting our latest work on the #genetics of neonatal jaundice, a project co-lead with Julius Juodakis, and a roller coaster of unexpected findings!

https://www.medrxiv.org/content/10.1101/2022.12.14.22283348v1

#Introduction

Hi #ScienceMastodon. We, at #J_Cell_Sci, are a #community journal covering all areas of #cellbiology. We also host the microscopy community site @focalplane_jcs. Journal of Cell Science is led by Editor-in-Chief Michael Way & published by the not-for-profit @Co_Biologists.

We will toot about our content, including #research papers, #reviews, #interviews, charitable activities, and news from @focalplane_jcs.

Toots by Senior Editor Petra Gross & Executive Editor @seemasainson

Hey there! I'm an Assistant Professor at #UCLA studying mouse and human #innateimmunity using #systemsimmunology and #crispr to find new targets for chronic viral infections, #T2D and #cancer. I mainly focus on #type1 immune responses including #NKcells #cDC1 and #ILC1. I started #earlycareerimmunology in 2021 to highlight underrepresented scientists early in their career. I'm here to post about #science, #art, #travel, #cat photos, and congratulate you on your wins 🥳🎉.

#HappyHanukkah to all who celebrate. Hope your light shines bright. 🕯️💙

Yeats on Immunology 🤯

PRPF31 #RetinitisPigmentosa is a #retinal disease caused by haploinsufficiency. #PRPF31 mutations are also homozygous lethal, which makes creating an animal model challenging. We tackled this problem by knocking out PRPF31 using a #CRISPR construct in adults using #AAV – and then showed that #GeneTherapy could prevent retinal degeneration in vivo. Out now in #NatureCommunications.

A sure sign that you celebrated the holidays with scientists. @Rahimilab

The lysosomal degraders

#PROTAC +derivatives

An update on Research & Commercialization of #MolecularGlue for targeted protein degradation

"LYTACs, ATACs, AbTACs, KineTACs, PROTABs, AUTACs, ATTECs and AUTOTACs"

Ken Garber Nature Biotech 2022
https://www.nature.com/articles/s41587-022-01594-7

Happy to block on Mastodon someone who accuses scientists for causing the pandemic, with no evidence or rationale whatsoever.

And happy to stay on Mastodon as their account is not amplified. #Science #twittermigration #CovidOrigin #disinformation

Hello world! I’ve joined and am looking forward to what this new platform has to offer!

Concentration #ArgentinaVsFrance

Excellent food for thought!
10 Simple Rules for a Supportive Lab Environment
https://direct.mit.edu/jocn/article/35/1/44/113591/10-Simple-Rules-for-a-Supportive-Lab-Environment