In this paper we describe a method to estimate a neighborhood containing a periodic orbit of a given system of two ordinary differential equations. By using the theory of integral averages, the system of differential equations can be transformed into an equivalent autonomous system which, by using the Hopf bifurcation theorem, the existence of a periodic solution of this autonomous nonlinear differential equations can be demonstrated. Using of this procedure it is possible to estimate an annular region where the orbit of the periodic solution is located. The method allows to improve the results that the Hopf Bifurcation provides on periodic solutions. In addition, some quantitative characteristics of the solution can be known, such as the amplitude, the period and, a region where the periodic orbit of the original system is located. The method is applied to a three-dimensional system of differential equations that models the competition of two predators and one prey, which under the assumption that the predators are equally voracious, property that in this case leads to a two-dimensional system, where all of the conditions of the method described here are easily applicable.