Andrew Kennard @askennard@qoto.org

collaboration with jn3008

Interested in how cells influence their neighbours?

Want a flexible, sensitive, unbiased approach to explore neighbour responses?

Tamina Lebek presents PUFFFIN: Positive Ultra-bright Fluorescent Fusion For Identifying Neighbours

PUFFFIN has SO MANY great features and we are very excited about using it to understand development, homeostasis, and disease

Here are some of the clever tricks that Tamina thought up to make this system so useful...

1/n

https://www.embopress.org/doi/full/10.1038/s44318-024-00154-w

I just found `alv` (https://github.com/arvestad/alv), a tool for viewing multiple sequence alignments on the command line, and it's perfect. I needed a tool to highlight differences and `alv -f fasta -t aa --only-variable aln.afa` does just that. Would prefer the numbering to start at 1 since sequence variants are 1-based #bioinformatics (Data from ERR031940.)

“In a way, the people our cars mow down are doing just as much as our highly paid programmers and engineers to create the utopian, safe streets of tomorrow. Each person who falls under our front bumper teaches us something valuable about how humans act in the real world.” #AI https://www.mcsweeneys.net/articles/our-self-driving-cars-will-save-countless-lives-but-they-will-kill-some-of-you-first?utm_source=werd.io&utm_campaign=mastodon&utm_channel=mastodon

Job ad for a colleague:

Postdoc on microscopy at the Bioengineering in Reproductive Health Research Group in Barcelona.

Open position for a postdoc with a background in optics and/or microscopy, to study human oocytes using hyperspectral imaging at #IBECBarcelona

https://ibecbarcelona.eu/es/postdoc-on-microscopy-at-the-bioengineering-in-reproductive-health-research-group/

#Barcelona #DevBio

Are there any microscopists hiding here?
Adding :AddBiophysicist to this post in order to get in the "Biophysicists on Mastodon" list...

#Biophysics #Microscopy #SMLM

a Portrait of Tenochtitlan, my 3D reconstruction of the capital of the Aztec Empire is released!

I've been looking forward to this for a long time, and I am really curious what all of you think.

Take a look:
http://tenochtitlan.thomaskole.nl

#tenochtitlan

I see a lot of people sharing blanket condemnations of all of those who still remain on #Twitter / #Xitter , and I need you to slow down a bit.

Sure, in some cases this is justified - journalists should really know better. But there are a lot of communities on that platform that are vital to many people's well-being that _haven't_ been replicated on the #Fediverse or elsewhere. Take #BlackTwitter - while #BlackMastodon is growing, it's still minuscule in comparison. The number of Twitter users in #Pakistan is staggering, while they are only a handful on #Mastodon . And so on, and so forth. Twitter was a lifeline to many marginalized people, and it still is - even though it gets worse every day - and we need to recognize this.

As a white European guy, it was easy for me to walk away from Twitter (I still have an account there, but I only post "you should go to Mastodon" stuff these days) - since it is easy to find people of a similar background to interact with. But this is NOT true for everyone!

So I'd like everyone to show a bit less contempt to the remaining Twitter users in general, and put some more effort in how to make the Fediverse friendlier to marginalized voices. Because there is MUCH work to be done here!

This is one of the most incredible pieces of research into a random piece of infrastructure I’ve ever seen. A wild ride.

https://tylervigen.com/the-mystery-of-the-bloomfield-bridge

h/t @danyork

🔬First method-focused work from our lab is just out in Cell Reports Methods 🎉
Interested in multicolor SMLM? Check the open-access final version of Karoline Friedl's PhD work, with Sandrine Lévêque-Fort's lab and the Abbelight gang
https://www.cell.com/cell-reports-methods/fulltext/S2667-2375(23)00215-1

Nothing destroys a graduate career faster than help avoidance.

For all the folks starting their #PhD (or their master thesis) today - a reminder why your PhD advisor can solve a problem so "easily" ...

#astrodon #academia #AcademiChatter #research

New @biorxivpreprint manuscript from my lab that sheds light on part of the dark genome, unannotated or poorly annotated genes in the genome. In it, we show that the highly conserved HEATR5 protein is a component of two biochemically distinct protein complexes.

https://www.biorxiv.org/content/10.1101/2023.08.24.554671v2

If you are a white leftist and you talk “both parties are the same they are both capitalist” you will loose most of your black audience. I think it ought to be obvious that this isn’t because blackfolks love Democrats (in most cases, there is always someone being simple in any group) —no. it’s because the difference between the parties is material and obvious and these are unstable times.

When I hear such talk I wonder if the speaker is working on voter suppression.

Fellow professors, if you're teaching an introductory course in graduate school, set aside some class time early in the semester for students to discuss their transition to your program. You'll find that they're struggling far more than you probably realized. You won't be able to solve all their problems, but opening space for them to voice their issues is more powerful than you can imagine.

#AcademicChatter #AcademicMastodon