Biomaterial based implants caused remote liver fatty deposition through activated blood-derived Kupffer cells https://www.biorxiv.org/content/10.1101/2023.04.12.536663v1?med=mas
Biomaterial based implants caused remote liver fatty deposition through activated blood-derived Kupffer cells https://www.biorxiv.org/content/10.1101/2023.04.12.536663v1?med=mas
@biorxivpreprint
^ "Natural-derived SF [silk fibroin] mesh showed acute & immune
responses in the short-term, but presented as safe & stable materials in the long-term. Synthetic
PP [polypropylene] is conventionally classified as an inert stable material; however, demonstrated sustained
“active” in vivo. ... The foreign
implants induced discomfort in patients and complaints usually occurred years post-surgery, such
as polyester mesh for hernia repair & silicone breast implants"