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Leaky gut syndrome - Wikipedia https://en.m.wikipedia.org/wiki/Leaky_gut_syndrome
Unlike the scientific phenomenon of increased intestinal permeability ("leaky gut"),[1][2] claims for the existence of "leaky gut syndrome" as a distinct medical condition come mostly from nutritionists and practitioners of alternative medicine.[1][3][4] Proponents claim that a "leaky gut" causes chronic inflammationthroughout the body that results in a wide range of conditions, including chronic fatigue syndrome, rheumatoid arthritis, lupus,migraines, multiple sclerosis, and autism.[1][3]As of 2016, there is little evidence to support the hypothesis that leaky gut syndrome directly causes this wide array of diseases.[1][5]
Leaky gut syndrome - Wikipedia
Leaky gut syndrome - Wikipedia
https://en.m.wikipedia.org/wiki/Leaky_gut_syndrome
The opening of intercellular tight junctions (increased intestinal permeability) allows uncontrolled passage of substances into the bloodstream, with subsequent possible development of immune and/or inflammatory reactions.[3][8]
https://en.m.wikipedia.org/wiki/Intestinal_permeability#Clinical_significance
A well studied model is celiac disease, in which increased intestinal permeability appears secondary to the abnormal immune reaction induced by gluten and allows fragments of gliadin protein to get past the intestinal epithelium, triggering an immune response at the intestinal submucosa level that leads to diverse gastrointestinal or extra-gastrointestinal symptoms.[25][26]