How Candida poaches host heme:
"While vacuolar function and the endocytic pathway were found to be essential for heme-iron utilization (Weissman et al., 2008), the mechanism for heme internalization into the cell was unknown. Here, we fill this gap, and identify a family of membrane proteins, previously classified as FREs based on sequence homology (Almeida et al., 2009; Baek et al., 2008), that are essential for heme uptake into the cell."