"In the early 1990s, two ideas were central to views of early eukaryotic evolution. One was that the “three domains tree of life” was an accurate description of the relationships between eukaryotes and prokaryotes (Woese et al. 1990). The other was that some anaerobic and/or parasitic microbial eukaryotes that branched at the base of eukaryotes in this tree were primitively without mitochondria because they split from other eukaryotes before the mitochondrial endosymbiosis (Cavalier-Smith 1987). I’ve spent most of the last 30 years testing these ideas, and, while it has often been difficult and frustrating, it has also been tremendously exciting and a lot of fun."
- T Martin Embley