'We use data on changes in the in vivo concentration of monoclonal antibodies, and the associated protection from COVID-19, over time to model the dose-response relationship of monoclonal antibodies for prophylaxis. We estimate that 50% protection from COVID-19 is achieved with a monoclonal antibody concentration of 939-fold of the in vitro IC50 (95% CI: 135 - 2073).'

#Preprint #MonoclonalAntibody #Covid#Covid19

https://www.medrxiv.org/content/10.1101/2022.11.22.22282199v1