'The underlying causes of this quadrupling in diabetes prevalence since the 1980s are multifaceted and include rapid urbanization, increased availability of highly processed, calorie-dense foods, and climate change, each of which has contributed to fundamental shifts in population-level dietary and physical activity behaviors. These shifts have resulted in perturbation of complex gene–environment interactions in populations that may have been previously naive to such risk factors. With approximately 75% of cases of type 2 diabetes occurring in low-income and middle-income countries (LMICs), this raging metabolic epidemic also highlights widening gaps in health inequities on a global scale.'

nature.com/articles/s41591-022

@cyrilpedia
What I find extra interesting is that we're now having a minor surge in late onset Type I due to COVID, and that can't be addressed by lifestyle changes. I don't know the actual numbers but it's significant enough for me to have seen well over 10 cases in a year.

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@warkittens I've heard a bit about this from other HCWs. Do you think some of it could be a batch effect from delayed diagnosis?

diabetesjournals.org/care/arti

@cyrilpedia
That's actually a really great hypothesis vs it being a COVID side effect. I think that's absolutely possible.

I'm extremely overtired right now, but there is involvement of the RAAS with COVID, so it definitely still could be causing some destruction / triggering immune reactions to the beta cells in the pancreas. In some cases.

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