"The virus-neutralizing activity of antibodies can be readily defined in robust in vitro assays and in passive transfer experiments. But to what degree vaccination-induced humoral immune responses prevent infection and pathogen replication also in humans, and therefore serve as indicators or even correlates of sterilizing immunity, cannot be easily established."
Wahl & Wardemann on #SterilizingImmunity (from Oct).
https://www.cell.com/immunity/fulltext/S1074-7613(22)00558-1