This is a great paper. A reminder - eukaryotes (cells with a nucleus) are a partnership between some likely motile predator cell and radical new "toxin exploiting" bacteria that not only could tolerate this new harsh chemical, molecular oxygen, in earth's atmophere, but use it.
RT @eLife@twitter.com
An ER phospholipid hydrolase drives ER-associated mitochondrial constriction for fission and fusion. https://elifesciences.org/articles/84279?utm_source=twitter&utm_medium=social&utm_campaign=organic
@ewanbirney we had an interesting conversation on the biological role of the fusion/fission cycle in #mitochondria with Orian Shirihai this summer on the #EMBOPodcast
It's about the Twig et al @embojournal paper that Nguyen & Voeltz cite in the opening of this @eLife piece:
"Cells maintain a characteristic mitochondrial architecture important for cellular metabolism and function. Mitochondria maintain their overall architecture and morphology by undergoing cycles of fission and fusion (Friedman et al., 2010; Twig et al., 2008; Youle and van der Bliek, 2012)."
https://www.embo.org/podcasts/fuse-or-die-a-conversation-with-orian-shirihai/