'Long-lasting sepsis-induced immunoparalysis has been principally studied in primary (1°) memory CD8 T cells; however, the impact of sepsis on memory CD8 T cells with a history of repeated cognate Ag encounters is largely unknown but important in understanding the role of sepsis in shaping the pre-existing memory CD8 T cell compartment.'

#immunology #Sepsis #CTL #cd8tcells

https://journals.aai.org/jimmunol/article-abstract/210/2/168/237582/Inefficient-Recovery-of-Repeatedly-Stimulated?redirectedFrom=fulltext