'To study TERT deregulation and its downstream consequences, we generated a Tert mutant promoter mouse model via CRISPR/Cas9 engineering of the murine equivalent locus (Tert-123C>T) and crossed it with thyroid-specific BrafV600E-mutant mice.'

#Preprint #Telomeres #telomerase

https://www.biorxiv.org/content/10.1101/2023.01.24.525280v1?med=mas