"Here we show that metabolic conditioning of CD8+ effector T cells induces an oxidized cellular redox balance at least in part mediated by increased mitochondrial reactive oxygen species (ROS). This redox shift contributes to enhanced in vivo persistence and tumor clearance."

#Preprint #Immunology #metabolism #TumorImmunology

https://www.biorxiv.org/content/10.1101/2023.03.27.533229v1